Real stories

The unique stories of thousands of real people living with HAE show that the outcomes are clear: ORLADEYO® works, the results last, and it’s easy to take

Real people taking ORLADEYO and their caregivers are outspoken about the difference it‘s made in their lives. Witness the change for yourself by hearing their stories.

Individual results may vary.

Leah, taking ORLADEYO® for hereditary angioedema (HAE) since she was 12

“Outside I said, I’m turning 12 today! But inside I said, I get ORLADEYO now. That made me so happy.”

Leah, on treatment since age 12

“The freedom that she, and we, have now that she’s on ORLADEYO is amazing.”

Natalie, mother and caregiver to Le’ah

Kissa, taking ORLADEYO® for HAE since 2018

“Since taking ORLADEYO, I’ve had fewer attacks and they are less severe.”

Kissa, on treatment since 2018

Individual results may vary

Kurtis, taking ORLADEYO® for HAE since 2021

“As long as we [have] our pill with us, the freedom is amazing.”

Kurtis, on treatment since 2021

Individual results may vary

Le'ah, taking ORLADEYO® for HAE since 2020

“[ORLADEYO] has exceeded any expectations that I could have had.”

Le’ah, on treatment since 2020

Angel, a person with HAE taking ORLADEYO®

“I would recommend ORLADEYO to other people with HAE.”

Angel, on treatment since age 15

Daryl, father and HAE caregiver to Le’ah, a person with HAE

“As a caregiver, you look at your child and you kind of breathe a sigh of relief.”

Daryl, father and caregiver to Le’ah

Individual results may vary

Hear from hereditary angioedema (HAE) experts who prescribe ORLADEYO

Dr. Lumry, a prescriber of ORLADEYO®

“Patients have indicated that they want an oral agent to treat their disease.”

Dr Lumry, a prescriber of ORLADEYO

Dr. Patricia Stewart, a prescriber of ORLADEYO®

“[My patients] feel like [ORLADEYO] is a medication that is both easy to take and controls their disease.”

Dr Patricia Stewart, a prescriber of ORLADEYO

Dr. Dixit, a prescriber of ORLADEYO®

“This has really allowed patients to live the kind of life they want to live.”

Dr Dixit, a prescriber of ORLADEYO

The #OrladeyoCommunity is growing and is here to help you feel empowered in your journey

Explore ORLADEYO and connect with a healthcare provider, patient ambassador, and others living with HAE.
Want to know more about our events?

ORLADEYO patient ambassadors

Meet Steve, an ORLADEYO® ambassador

Meet Steve

Meet Kelly, an ORLADEYO® ambassador

Meet Kelly

Meet Heidi, an ORLADEYO® ambassador

Meet Heidi

Meet Le’ah, an ORLADEYO® ambassador

Meet Le’ah

Meet Kissa, an ORLADEYO® ambassador

Meet Kissa

Meet Elaine, an ORLADEYO® ambassador

Meet Elaine

Meet Myrtle, an ORLADEYO® ambassador

Meet Myrtle

Meet Natalie, an ORLADEYO® ambassador

Meet Natalie

Meet Kurtis, an ORLADEYO® ambassador

Meet Kurtis

Meet Rochelle, an ORLADEYO® ambassador

Meet Rochelle

It‘s important to advocate for what you want out of preventative
treatment so that you don‘t have to compromise on your goals.

Download the discussion guide and use it to talk to your healthcare provider about where you are in your journey, your satisfaction with your current treatment plan, and if ORLADEYO may be right for you.

Currently taking preventative HAE therapy

Currently taking preventative therapy

Not yet taking preventative HAE therapy

Not yet taking preventative therapy

Looking for support?


WHAT IS ORLADEYO® (berotralstat)?

ORLADEYO (or-luh-DAY-oh) is a prescription medicine used to prevent attacks of hereditary angioedema (HAE) in adults and children 12 years of age and older. It is not known if ORLADEYO is safe and effective in children under 12 years of age.

It is not known if ORLADEYO is safe and effective to treat an acute HAE attack, therefore ORLADEYO should not be used to treat an acute HAE attack.

Do not take more than one capsule of ORLADEYO per day because extra doses can cause heart rhythm problems.


Before taking ORLADEYO, tell your healthcare provider about all of your medical conditions, including if you

  • have liver problems or are on kidney dialysis.
  • are pregnant or planning to become pregnant. It is not known if ORLADEYO can harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if ORLADEYO passes into your breastmilk. Talk to your healthcare provider about the best way to feed your baby while taking ORLADEYO.

Tell your healthcare provider about all of the medicines you take, including other medicines for HAE, prescription and over-the-counter medicines, vitamins, and herbal supplements.

Taking ORLADEYO with certain other medicines may affect the way other medicines work and other medicines may affect how ORLADEYO works.

Know the medicines you take and keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

What are the possible side effects of ORLADEYO?

Taking more than one capsule of ORLADEYO per day may cause serious side effects, including heart rhythm problems. A heart rhythm problem called QT prolongation can happen in people who take more than one capsule of ORLADEYO per day. This condition can cause an abnormal heartbeat. Do not take more than one capsule of ORLADEYO per day.

The most common side effects of ORLADEYO include abdominal pain, vomiting, diarrhea, back pain, and heartburn. These are not all of the possible side effects of ORLADEYO. For more information, ask your healthcare provider or pharmacist.

Talk to your healthcare provider for medical advice about side effects.

You are encouraged to report side effects of prescription drugs to BioCryst Pharmaceuticals, Inc at 1-833-633-2279 or to the FDA at or 1-800-FDA-1088.

For more information, please see the full Prescribing Information including the Patient Information.